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  • This method takes as input an antibody heavy and light chain and returns models of the antibody fV fragment.  The Single Chain HM API is a more suitable approach for modeling nanobodies and non-antibody proteins.

DDG is a tool for predicting the energetic consequences of single mutations. It approximates the Gibbs free energy change of folding of the native vs. point mutant.

Disulfidizer is a tool for searching for disulfides.  Given an input structure it will attempt to sample disulfides that might exist.  This is appropriate for:

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